IMMUNE REACTION AGAINST CYTOSKELETON IN COELIAC DISEASE
نویسندگان
چکیده
منابع مشابه
Immune reaction against the cytoskeleton in coeliac disease.
BACKGROUND The cytoskeleton actin network of intestinal microvilli has been found to be rapidly impaired after gluten challenge in coeliac disease (CD). The aim of this study was to investigate the presence of an immune reaction towards cytoskeleton structures such as actin filaments in CD. METHODS Eighty three antiendomysial antibody positive CD patients (52 children and 31 adults) were stud...
متن کاملBreast milk against coeliac disease.
Coeliac disease is a multifactorial disorder developing as a result of a complex interplay between genetic and environmental factors. HLA and non-HLA genes are involved, and gluten is obviously a critical environmental factor as the disease goes into remission when gluten is eliminated from the diet. The important case control study by Ivarsson et al concludes that feeding with breast milk when...
متن کاملCOELIAC DISEASE Elevation of IgG antibodies against tissue transglutaminase as a diagnostic tool for coeliac disease in selective IgA deficiency
Background: IgA serum autoantibodies against tissue transglutaminase (tTG) have an established diagnostic value in coeliac disease, and high efficacy tests are widely available for their detection. However, serological evaluation of IgA deficient subjects is still difficult. Aims: To evaluate the diagnostic potential of IgG class anti-tTG autoantibodies measured quantitatively using an enzyme l...
متن کاملGenetics in coeliac disease.
Coeliac disease has a strong genetic component, higher than for many other common complex diseases. Possession of the HLA-DQ2 variant is required for presentation of disease causing dietary antigens to T cells, although this is also common in the healthy population. Non-HLA genetic factors account for the majority of heritable risk. Linkage studies have identified promising regions on chromosom...
متن کاملAdvances in coeliac disease.
PURPOSE OF REVIEW The number of people diagnosed with coeliac disease continues to rise, and this article critically summarizes recent research into the condition. RECENT FINDINGS Much work has been focused on clarifying the molecular pathways involving cytokines in coeliac disease. Such work will yield improved understanding of the complex pathogenesis of coeliac disease and novel therapeuti...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Pediatric Gastroenterology & Nutrition
سال: 1999
ISSN: 0277-2116
DOI: 10.1097/00005176-199905000-00050